ABSTRACT

   Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.



        

Key words:
Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
September 2011 Issue
September- 2011 / Volume - 3/Issue - 07
( Total Articles =25)
1. CLARITHROMYCIN AND RABEPRAZOLE MUCOADHESIVE MICROSPHERES FOR ANTI HELICOBACTER PYLORI THERAPY: FORMULATION AND INVITRO EVALUATION
Aijaz A. Sheikh**    [ Abstract ] -- [ Full Text - PDF ]

2. ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ZIDOVUDINE, LAMIVUDINE AND NEVIRAPINE TABLETS BY RP-HPLC
K.Anand Babu*    [ Abstract ] -- [ Full Text - PDF ]

3. DETERMINATION OF CARVEDILOL IN HUMAN PLASMA BY RP-HPLC METHOD WITH ULTRAVIOLET DETECTION
Ch. Ajay Babu*    [ Abstract ] -- [ Full Text - PDF ]

4. ABSORPTION RATIO METHOD FOR THE ESTIMATION OF MOXIFLOXACIN HCl & KETOROLAC TROMETHAMINE IN THEIR COMBINED DOSAGE Form by UV-Visible Spectroscopy
Gandhi L.R.*    [ Abstrct ] -- [ Full Text - PDF ]

5. TRADITIONAL PLANT REMEDIES FOR PUBLIC HEALTH IN NAWANSHAHAR DISTRICT OF PUNJAB
M. C. Sidhu1*    [ Abstract ] -- [ Full Text - PDF ]

6. TASTE MASKING BY INCLUSION COMPLEXATION: A REVIEW
Manali S. Mulay*    [ Abstract ] -- [ Full Text - PDF ]

7. FORMULATION AND EVALUATION OF LORAZEPAM FAST DISSOLVING TABLETS
Mayank Patel*    [ Abstract ] -- [ Full Text - PDF ]

8. COMPARATIVE STUDY OF DOSSIER FILE SUBMISSION PROCESS OF DRUG PRODUCT IN USA AND EUROPE
Devesh Sharma*    [ Abstract ] -- [ Full Text - PDF ]

9. CHEMICAL PENETRATION ENHANCERS: AN APPROACH FOR BETTER TRANSDERMAL DRUG DELIVERY
Saurabh Kumar*    [ Abstract ] -- [ Full Text - PDF ]

10. FORMULATION AND IN VITRO EVALUATION OF LOSARTAN POTASSIUM FLOATING TABLETS

A. Suman*    [ Abstract ] -- [ Full Text - PDF ]

11. LIPID-BASED NANOPARTICULATE DRUG DELIVERY SYSTEMS: AN OVERVIEW

Threveen Challa*    [ Abstract ] -- [ Full Text - PDF ]

12. DIFFERENTIAL MORPHOLOGICAL CHANGES AND EXPRESSION STUDIES OF GFAP IN GLIOMA INDUCED IN RATS FOLLOWING SESAMOL TREATMENT
Rangarajan Narasimhan*    [ Abstract ] -- [ Full Text - PDF ]

13. A COMPARATIVE STUDY ON THE EFFECTS OF HERBAL AND CONVENTIONAL MEDICINE ON CARDIO VASCULAR DISEASE
Thirunethiran Karpagam*    [ Abstract ] -- [ Full Text - PDF ]

14. FIBRATES THE BEST MODIFYING STRATEGY FOR DYSLIPIDEMIAS : A REVIEW
Gurfeth Singh*    [ Abstract ] -- [ Full Text - PDF ]

15. SYNTHESIS OF SOME NEW SCHIFF’S BASES OF QUINOXALINE-2(1H)-ONE AS POTENT ANTI-INFLAMMATORY AGENTS
Ghadage Ratnadeep V.*    [ Abstract ] -- [ Full Text - PDF ]

16. DETERMINATION OF SODIUM, POTASSIUM, CHROMIUM AND ZINC IN MEDICINAL PLANTS USING INSTRUMENTAL NEUTRON ACTIVATION ANALYSIS (INAA)
P.Mamatha*    [ Abstract ] -- [ Full Text - PDF ]

17. TRANSDERMAL DELIVERY OF ACYCLOVIR WITH RESPECT WITH EFFECT OF TERPENE
Sudarshan S. Joshi*    [ Abstract ] -- [ Full Text - PDF ]

18. CHEMICAL STANDARDISATION STUDIES ON CARDIOSPERMUM HALICACABUM LINN
K.Sughuna*    [ Abstract ] -- [ Full Text - PDF ]

19. FORMULATION AND IN-VITRO EVALUATION OF DILTIAZEM HYDROCHLORIDE MATRIX TABLETS FOR COLONIC DRUG DELIVERY
V. V. Rajguru*    [ Abstract ] -- [ Full Text - PDF ]

20. ANTIULCER ACTIVITY OF METHANOLIC FRUIT EXTRACT OF LAGENARIA SICERARIA (MOL.)
Vivek srivastava*    [ Abstract ] -- [ Full Text - PDF ]

21. PHARMACEUTICAL APPLICATIONS OF MAGNETIC PARTICLES IN DRUG DELIVERY SYSTEM
Priyanka Lokwani*    [ Abstract ] -- [ Full Text - PDF ]

22. DIURETIC ACTIVITY OF TECTONA GRANDIS LEAVES AQUEOUS EXTRACT IN WISTAR RATS
Kore K.J.*    [ Abstract ] -- [ Full Text - PDF ]

23. METHOD DEVELOPMENT, VALIDATION OF VALSARTAN IN BULK AND PHARMACEUTICAL DOSAGE FORMS BY ISOCRATIC RP-HPLC TECHNIQUE
Kishanta Kumar Pradhan*    [ Abstract ] -- [ Full Text - PDF ]

24. FORMULATION, DEVELOPMENT AND IN VITRO EVALUATION OF SUSTAINED RELEASE MATRIX TABLET OF STAVUDINE

R. Mathurkar*    [ Abstract ] -- [ Full Text - PDF ]

25. METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS DETERMINATION OF EBASTINE AND PHENYLEPHRINE HYDROCHLORIDE IN TABLET FORMUALTION BY RP- HPLC

R.S.Wagh*    [ Abstract ] -- [ Full Text - PDF ]