ABSTRACT

   Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.



        

Key words:
Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
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Adebiyi, Adedayo B.1*
*Sheda Science and Technology Complex, PMB 186 Garki, Abuja, Nigeria.
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2.
ELABORATIVE SLANT ON LIPIDS, HYPERLIPIDEMIA, AND BILE ACID BINDING RESINS
Dr. Hasan Raza*
*Assistant Professor of Biochemistry, LM&DC, Lahore, Pakistan.

[ Abstract ] -- [ Full Text - PDF ]

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*
Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
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*Anuradha College of Pharmacy, Chikhli, Maharashtra, India
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*
1 Sri Lakshmi Narasimha College of Pharmacy, Chittoor, A.P., India  
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*
University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, A.P, India.
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Manjusha Patankar*
*
Department of Pharmacology, Dr.DY Patil Medical College, Navi Mumbai, India
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Royal College of pharmacy and Health Sciences, Andhapasara Road, Berhampur, Odisha.
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.*
*
Kanchi Mamunivar Centre for Post graduate studies, Lawspet, Pondicherry 605 008, India   
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*
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Suneel Kumar Kapubalu*
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PharmaZell R&D (India) Private Limited, Visakhapatnam-531 162, India
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Gupta M.M*
*
Dept. of  Pharmaceutics, Jaipur college of Pharmacy, Sitapura, Jaipur, India
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*   
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Bhargavi Moturi*   
*
Centre for Biotechnology, Jawaharlal Nehru Technological University, Hyderabad , AP, India.
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A.P.Purohit
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*
Dept. of Pharmacognosy, BV's Poona College of Pharmacy, Pune-411038, India.
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*
Dept. of Pharmacy, Rameshwaram Institute of Technology & Management, Lucknow, UP, India
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JSS College of Pharmacy, Rockland, Ootacamund, Tamil Nadu, India.
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*
B.Pharmacy College,Rampura,Kakanpur,Godhra-389001,Gujrat,India
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Department of Botany, Govt. Arts College, Thiruvannamalai - 606 603, Tamil Nadu, India
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Sopan P. Wadhe*   
*
Pataldhamal Wadhwani College Of Pharmacy Yavatmal, India.
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*
Dept. of Pharmaceutics, Vinayaka Missionís College of Pharmacy, Salem - 636 008, TN, India
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*
Dept. of Pharmaceutics, College of Pharmacy, Chincholi, Sinnar, Nashik, MH, India
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*
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November 2011 Issue
November- 2011 / Volume - 3/Issue - 09
( Total Articles =25)