ABSTRACT

   Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.



        

Key words:
Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
ABSTRACT

   Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.



        

Key words:
Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
Copyright © 2009  by "International Journal of Pharmaceutica Research and Development"  ·  All Rights reserved  ·  E-Mail: info@ijprd.com
Welcome to "International Journal of Pharmaceutical Research and Development"  i.e. "IJPRD"
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Online Since : March 2009
TODAY IS
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
1. PHARMACOGNOSTIC AND PHYTOCHEMICAL STUDIES ON THE FLOWERS OF PUNICA GRANATUM (L)
Akhilesh Kumar Tripathi1*
*Guru Ramdas Khalsa Institute of Science and     Technology (Pharmacy), Dist: Jabalpur, (M.P.), India
[ Abstract ] -- [ Full Text - PDF ]

2.
INVESTIGATIONS ON THE NOOTROPIC POTENTIAL OF CALOTROPIS PROCERA IN MICE
Hanumanthachar Joshi*

*Sarada Vilas College of Pharmacy, Mysore-570 004, Karnataka

[ Abstract ] -- [ Full Text - PDF ]

3.
ANTIBACTERIAL PROPERTIES OF PSIDIUM GUAJAVA LEAVES, FRUITS AND STEMS AGAINST VARIOUS PATHOGENS
Amit Pandey*
*
MRD LifeSciences ,Lucknow  instead of Indore Institute Of Pharmacy,Indore, MP, India
[ Abstract ] -- [ Full Text - PDF ]

4.
TRANSDERMAL APPROACH OF ANTIDIABETIC DRUG GLIBENCLAMIDE:A REVIEW
Ankit Sharma*  

*Department of Biotechnology & Biochemistry, Avinashilingam University for Women,
Coimbatore-641043, TN, India
[ Abstrct ] -- [ Full Text - PDF ]

5.
FORMULATION AND EVALUATION OF FLOATING DRUG DELIVERY SYSTEM OF CIPROFLOXACIN
Bhalchandra M. Habade *
*Shivajirao S. Jondhale College of Pharmacy, Aasangaon-421601 Dist:-Thane,
State: - Maharashtra, India.

  [ Abstract ] -- [ Full Text - PDF ]

6.
THE MICROCHIP DEVICE DESIGN FOR CONTROLLED-RELEASE DRU DELIVERY SYSTEM -A REVIEW
Dharmendra S. Sisodiya*
*
B.N. collage of pharmacy, udaipur, India
[ Abstract ] -- [ Full Text - PDF ]

7.
PROGRESSIVE EFFECT OF KESARI POWDER ON DIFFERENT HAEMATOLOGICAL AND SEROLOGICAL PARAMETERS IN FEMALE WISTAR RATS
Ms.Divya.C.V
*
*
Dr.N.G.P Arts and Science College, Coimbatore-641048, TamilNadu, India
[ Abstract ] -- [ Full Text - PDF ]

8.
A COMPREHENSIVE REVIEW ON BUCCAL DRUG DELIVERY SYSTEM
Md. Habban Akhter*
*
Institute of Pharmaceutical Research, GLA university, Mathura 281 406 (U.P), India
[ Abstract ] -- [ Full Text - PDF ]

9.
VALIDATED SPECTROPHOTOMETRIC ESTIMATION OF LACOSAMIDE IN BULK AND TABLET DOSAGE FORMS
K.Sai Sumanth*
*
Bharathi College of Pharmacy,Bharathinagara-571422, Karnataka, India.
[ Abstract ] -- [ Full Text - PDF ]

10.
DESIGN, DEVELOPMENT AND IN VITRO CHARACTERIZATION OF DILTIAZEM BUCCOADHESIVE TABLET
Madhuri A. Channawar*
*
Pataldhamal Wadhwani College of Pharmacy Yavatmal -442001, India  
[ Abstract ] -- [ Full Text - PDF ]

11.
DEVELOPMENT AND EVALUATION OF SOLID DISPERSION FORMULATED IBUPROFEN TABLETS USING CYCLO DEXTRINS AS CARRIER
Meka Anand Kumar
*
*
G.Pulla Reddy College of Pharmacy, Mehdipatnam, Hyderabad, Andhra Pradesh, India.   
[ Abstract ] -- [ Full Text - PDF ]

12.
GLUCOSAMINE SULPHATE TRANSDERMAL GELS: AN ALTERNATIVE ROUTE FOR DRUG DELIVERY
Alaa Mohammad Abdel Azim*
*
Department of Toxic and Narcotic Drug Forensic Medicine, Cairo, Egypt.
[ Abstract ] -- [ Full Text - PDF ]

13. PHYTOCHEMICAL INVESTIGATION AND STUDY OF ANTI-NFLAMMATORY ACTIVITY OF MORINGA OLEIFERA LAM.
Mohammed Rageeb Mohammed Usman.*
*
Ph.D Research Scholars JJT University, Jhunjhunu, Rajasthan, India, 333001
[ Abstract ] -- [ Full Text - PDF ]

14.
IN VITRO ANTIBACTERIAL ACTIVITY OF AEGICERAS CORNICULATUM AND BRUGUIERA CYLINDRICA AGAINST ISOLATED BACTERIAL URINARY TRACT INFECTIONS
GEEGI P G
*   
*Department of Biochemistry, St. Joseph’s College (Autonomous),Tiruchirappalli -02,TN, India
[ Abstract ] -- [ Full Text - PDF ]

15.
INSECTICIDAL ACTIVITY OF ACETONE CRUDE EXTRACT OF SPHAERANTHUS INDICUS LIN. (FAMILY-ASTERACEAE)  CALLOSOBRUCHES MACULATUS
Rajni Shrivastava *   
*
Department of Zoology, Govt. P.G. College, BHEL, Bhopal (M.P.), India
[ Abstract ] -- [ Full Text - PDF ]

16.
A BRIEF REVIEW OF PLANTS HAVING ANTI CANCER PROPERTY
Prushin Thakore
*   
*
1.Department of pharmacology, East point College of Pharmacy, Bangalore-560 049
[ Abstract ] -- [ Full Text - PDF ]

17.
CARDIOPROTECTIVE NATURE OF N-ACETYL CYSTEINE AGAINST BETA ADRENERGIC AGONIST INDUCED MYOCARDIAL INFARCTION IN RATS
Shanmugapriya A
, *   

*
Department of Bio chemistry Shrimathi Indira Gandhi College, Trichirapalli, Tamil Nadu, India
[ Abstract ] -- [ Full Text - PDF ]


18. RECENT ADVANCES IN RESEARCH OF ANTIULCER DRUG OF NATURAL ORIGIN : A REVIEW
Yogesh Sopan Lawande*   
*
Sinhgad Institute of Pharmaceutical Sciences, Lonavala, Pune -401410, Maharashtra, India.
[ Abstract ] -- [ Full Text - PDF ]


19. ANTIBACTERIAL ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF OCIMUM GRATISSIMUM L.
Thirunethiran Karpagam1*   
*
Department of Biochemistry, Shrimati Indira Gandhi College, Tiruchirappalli - 620 002, (INDIA)
[ Abstract ] -- [ Full Text - PDF ]


20. THE PROTECTIVE ROLE OF BENINCASA HISPIDA ON DICLOFENAC SODIUM INDUCED HEPATOTOXICITY IN ALBINO RAT MODEL
Dr. Shyamal K. Das1*   
*
Department of Physiology, Krishnath  College, University of Kalyani, Berhampore, Murshidabad,IN
[ Abstract ] -- [ Full Text - PDF ]


21.
MULTIPLE UNIT SUSTAINED RELEASED FLOATING MICROBALOONS OF KETOROLAC: FORMULATION, IN-VITRO AND IN-VIVO EVALUATION
Navneet Nagpal1*   
*
Department of Pharmaceutics, Khalsa College of Pharmacy, Amritsar,Punjab,India
[ Abstract ] -- [ Full Text - PDF ]

22.
SYNTHESIS, CHARACTERISATION AND BIOLOGICAL ACTIVITY OF O-BENZOYL BENZOIC ACID AND O-BENZOYL- N-2-PYRIDYL BENZAMIDE METAL COMPLEXES
Valli. G.*   
*
Department of chemistry, S.F.R.College for Women, Sivakasi-626123.India
[ Abstract ] -- [ Full Text - PDF ]

23.
DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHODS FOR ESTIMATION OF ALFUZOSIN IN BULK AND PHARMACEUTICAL FORMULATION
Adsule Prajakta V.
*   
*
MAEER’S Maharashtra Institute of Pharmacy, MIT campus, Paud Road, Kothrud, Pune - 411 038, MH.,India
[ Abstract ] -- [ Full Text - PDF ]

24.
SOLID LIPID NANOPARTICLES; THE BENEFICIAL CARRIER FOR THE DELIVERY OF LIPID SOLUBLE DRUGS
Pawar Bhima B.
*   
*
Department Of Pharmaceutics, Institute Of Pharmaceutical Education, Boradi, MH.,India
[ Abstract ] -- [ Full Text - PDF ]


25.
IN VITRO ANTIMICROBIAL ACTIVITY OF EXTRACTS OF PLANTS OF GENUS SIDA LINN.
Rajesh R. Wake
*   
*
Lokseva College of Pharmacy, Phulgaon, Maharashtra, India.
[ Abstract ] -- [ Full Text - PDF ]


26.
ENVIRONMENTALLY RESPONSIVE OPTHALMIC GEL FORMULATION: BASED ON COMBINATION WITH NATURAL POLYCATIONIC COPOLYMER
Mitali  M. Bodhankar
*   
*
Department of Pharmaceutics, Gurunanak College of Pharmacy, Behind C.P. Foundry, Nari Road, Nagpur-440 026.MH,India.
[ Abstract ] -- [ Full Text - PDF ]

27.
NANOTECHNOLOGY: A NEW TOOL FOR AIDS TREATMENT-A REVIEW
Bhushan D.Tade
*   
*
Department of Pharmaceutics, Institute of Pharmaceutical Education, Boradi - 425428, Tal-Shirpur, Maharashtra, India
[ Abstract ] -- [ Full Text - PDF ]

28.
TABLETING OF COATED MULTIPARTICULATES: A REVIEW
Vijayendrakumar Redasani*   
*
Working in Formulation Research and Development at Inventia Healthcare Pvt. Ltd., India (*Research Scholar at Jawaharlal Nehru Technical University, Hyderabad)
[ Abstract ] -- [ Full Text - PDF ]


29.
FORMULATION AND EVUALATION OF BUCCAL BIOADHESIVE TABLET OF ACYCLOVIR BY USING SPRAY-DRIED AMIOCA STARCH/CARBOPOL 940P MIXTURE
Jadhav S.D.*   
*
TVES’s Hon’ble Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur , Tq: Yawal, Dist: Jalgaon.MH.,India
[ Abstract ] -- [ Full Text - PDF ]


January 2012 Issue
January- 2012 / Volume - 3/Issue - 11
( Total Articles =29)