ABSTRACT

   Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.



        

Key words:
Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
ABSTRACT

   Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.



        

Key words:
Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
Copyright © 2009  by "International Journal of Pharmaceutica Research and Development"  ∑  All Rights reserved  ∑  E-Mail: info@ijprd.com
Welcome to "International Journal of Pharmaceutical Research and Development"  i.e. "IJPRD"
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What's New | Feedback | Copyright and Disclaimer
Online Since : March 2009
TODAY IS
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
1. COMPARATIVE ANALYSIS OF METALLIC ELEMENTS AMONG MENOPAUSAL, PREGNANT AND UN MARRIED FEMALES BY USING FINGERNAILS
Aima Iram Batool1*
*Department of Biological Sciences University of Sargodha,Punjab,Pakistan
[ Abstract ] -- [ Full Text - PDF ]

2.
COMPARISON OF LIPID LOWERING EFFECTS OF NIGELLA SATIVA AND GEMFIBROZIL
Ghazi Mahmood*

*Multan Medical & Dental College, Multan, Pakistan

[ Abstract ] -- [ Full Text - PDF ]

3.
EVALUATION OF ANTI-DIARRHOEAL POTENTIAL OF METHANOL EXTRACT OF Garcinia kola STEM BARK
Kagbo, H. D.*
*
Faculty of Basic Medical Sciences,College of Health Sciences, University of Port Harcourt, Nigeria
[ Abstract ] -- [ Full Text - PDF ]

4.
IN-VITRO EVALUATION OF THE ANTIFUNGAL ACTIVITY OF LEAF EXTRACTS OF MESUA NAGASSARIUM (BURM.F.) AND KIGELIA PINNATA.
Md. Masud Pervez*  

*Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
[ Abstrct ] -- [ Full Text - PDF ]

5.
STUDY OF DISSOLUTION ENHANCEMENT PROPERTY OF POLOXAMER 407 USING BCS CLASS II DRUGS
Rajibul Islam Khan*
*University of Asia Pacific, H/N: 73, R/N: 5A, Dhanmondi R/A, Dhaka-1209, Bangladesh
  [ Abstract ] -- [ Full Text - PDF ]

6.
SINGLE BLIND PLACEBO CONTROLLED COMPARATIVE STUDY OF HYPOLIPIDEMIC EFFECTS OF KALONJI AND ATORVASTATIN
Shah Murad*
*
Lahore Medical & Dental College, Lahore, Pakistan
[ Abstract ] -- [ Full Text - PDF ]

7.
A COMPARATIVE ANALYSIS OF ANTIBACTERIAL PROPERTIES OF DIFFERENT VARIETIES OF ROSA INDICA LEAVES AND PETALS AGAINST VARIOUS PATHOGENS
Amit Pandey
*
*
R&D Division, MRD LifeSciences, Lucknow-226010, India
[ Abstract ] -- [ Full Text - PDF ]

8.
ACYLATED CHITOSAN: A PROMISING CARRIER IN NOVEL DRUG DELIVERY OF ALBENDAZOLE
Anuradha Rathore*
*
Swami Vivekananda College of Pharmacy, Near Toll Naka, Khandwa Road, Indore-452020
[ Abstract ] -- [ Full Text - PDF ]

9.
FORMULATION OF SUSTAINED RELEASE TABLET OF ANTI OBESITY DRUG GARCINIA CAMBOGIA
Atul Sethi*
*
Indore Institute of Pharmacy (IIP) Indore Rau-Pithampur Road Indore (M.P.)
[ Abstract ] -- [ Full Text - PDF ]

10.
A SIMPLE ELECTROANLYTICAL METHOD FOR ESTIMATION OF ROSIGLITAZONE MALEATE AND METFORMIN HYDROCHLORIDE INDIVIDUALLY FROM PHARMACEUTICAL FORMULATION
Shrotri C.K. *
*
Department Of Chemistry, Ramnarain Ruia College, Matunga  (East), Mumbai-19.  
[ Abstract ] -- [ Full Text - PDF ]

11.
PREPARATION AND EVALUATION OF HPMC-ALGINATE MUCOADHESIVE MICROCAPSULES OF ACECLOFENAC FOR CONTROLLED RELEASE
Prof. K.P.R. Chowdary
*
*
University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam.   
[ Abstract ] -- [ Full Text - PDF ]

12.
IN SILICO DOCKING STUDIES OF STAPHYLOCOCCUS AUREUS VIRULENT PROTEINS WITH ANTIMICROBIAL PEPTIDES
Subashree Venugopal*
*
Biomolecules and Genetics School of Biosciences and Technology VIT University Vellore-632014
[ Abstract ] -- [ Full Text - PDF ]

13. ANTIFERTILITY EFFECT OF HYDRO-ALCOHOLIC EXTRACT OF CISSAMPELOS PAREIRA LINN.ON MALE ALBINO RATS
Harisha B.*
*
Gautham College of Pharmacy, RT Nagar, Bangalore-560032, Karnataka, India.
[ Abstract ] -- [ Full Text - PDF ]

14.
HPLC METHOD OF DETECTION FOR 5ASA IN PURE AND IN TABLETS
Lalit Jejurkar
*   
*Vidyabharti College of Pharmacy, Department of P.G. & Research, Amravati-444602,MH, India
[ Abstract ] -- [ Full Text - PDF ]

15.
NIOSOMES: AN STUDY ON NOVEL DRUG DELIVERY SYSTEM-A REVIEW
Navneet Kumar Verma *   
*
Rameshwaram Institute of Technology and Management, Lucknow (U.P), India
[ Abstract ] -- [ Full Text - PDF ]

16. THE FLOATING DRUG DELIVERY SYSTEM AND IT`S IMPACT ON CALCIUM CHANNEL BLOCKER:A REVIEW ARTICLE
Nirav Rabadia
*   
*Jaipur National University, Jagatpura-Jaipur, RJ, India
[ Abstract ] -- [ Full Text - PDF ]


17.
PHYTOCHEMICAL AND BIOCHEMICAL ANALYSIS OF THE PLANT EXTRACT OF ACACIA CONCINNA (WILD)
A. Xavier Vergeese Raja
*   

*
Department of Biotechnology, Karpagam University, Coimbatore-21, India.
[ Abstract ] -- [ Full Text - PDF ]


18. SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW 2,5-DISUBSTITUTED 1,3,4-THIADIAZOLE DERIVATIVES.
Suresh Sharabasappa*   
*
KLEíS College of Pharmacy, Vidyanagar, Hubli-580 031 Karnataka, India.
[ Abstract ] -- [ Full Text - PDF ]


19. EVALUATION OF PRELIMINARY PHYTOCHEMICAL PROPERTIES AND ANTIBACTERIAL ACTIVITY OF THE EXTRACT OF MUSA ROSACEA
Srikanth.M1*   
*
A.U College of Pharmaceutical Sciences, Andhra University, Visakhapatnam 530 003.
[ Abstract ] -- [ Full Text - PDF ]


20. ANTIMICROBIAL POTENTIAL OF ACTINOMYCETES AGAINST MICROBES ISOLATED FROM AYURVEDIC DRUGS
Padma Singh1*   
*
Microbiology Department , Kanya Gurukul Mahavidyalaya , Gurukul Kangri University , Uttarakhand , India
[ Abstract ] -- [ Full Text - PDF ]


21. ANIMAL MODELS FOR TYPE-2 DIABETES MELLITUS: A REVIEW
S. N. Manjula*   
*
J.S.S. College of Pharmacy, Department of Pharmacology, Sri Shivrathreeshwara Nagara, and Mysore-15, India
[ Abstract ] -- [ Full Text - PDF ]

22. NOVEL SUATAINED RELEASE DRUG DELIVERY SYSTEM: REVIEW
K.N. Khachane1*   
*
P.S.G.V.P.Mís College of Pharmacy Shahada,Dist-Nandurbar, Maharashtra-425 409, India
[ Abstract ] -- [ Full Text - PDF ]

23. STUDY OF POTENTIAL OF A NATURAL POLYMER AS A FORMULATION COMPONENT FOR THE DEVELOPMENT OF SUSTAINED RELEASE MATRIX TABLET
Rahul Thube1*   
*
Jodhpur National University, Jodhpur, Rajasthan, India-342003
[ Abstract ] -- [ Full Text - PDF ]

24. DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR THE DETERMINATION OF CINITAPRIDE BY USING UV-DETECTION METHOD
D.Samson Israel1*   
*
University College of Pharmaceutical Sciences, Andhra University, Hydrabad, AP, India
[ Abstract ] -- [ Full Text - PDF ]
February 2012 Issue
February - 2012 / Volume - 3/Issue - 12
( Total Articles =24)