ABSTRACT

   Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.



        

Key words:
Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
August 2011 Issue
August - 2011 / Volume - 3/Issue - 06
( Total Articles =38 )
1. POLYPHARMACY IN ELDERLY PATIENTS AT DISCHARGE MEDICATION
Abdul Nazer Ali *    [ Abstract ] -- [ Full Text - PDF ]

2. DEVELOPMENT OF ENTERIC COATED PECTIN MATRIX TABLETS OF METRONIDAZOLE FOR COLON TARGETING
Bala Venkata Pradeep.V*    [ Abstract ] -- [ Full Text - PDF ]

3. FORMULATION AND EVALUATION OF FAST DISINTEGRATING TABLET OF DICLOFENAC SODIUM
Bhavesh J. Vaghela*    [ Abstract ] -- [ Full Text - PDF ]

4. MACROSCOPICAL, MICROSCOPICAL AND PHYSICO-CHEMICAL ANALYSIS OF THE ROOT OF CASSIA TORA LINN.(CAESALPINIACEAE)
Chandan Das*    [ Abstrct ] -- [ Full Text - PDF ]

5. IN VITRO ANTIBACTERIAL AND ANTIFUNGAL EVALUATION OF VALLARIS SOLANACEA (ROTH) KUNTZE
H.M. Vagdevi1*    [ Abstract ] -- [ Full Text - PDF ]

6. VALIDATED HPTLC CONTENT UNIFORMITY TEST FOR THE DETERMINATION OF DIAZEPAM IN TABLET DOSAGE FORM
Vaishali P. Machale*    [ Abstract ] -- [ Full Text - PDF ]

7. ANALYSIS OF HUMAN SERUM WITH VARIOUS CATARACTS BY INDUCTIVELY COUPLED PLASMA ATOMIC EMISSION SPECTROMETRY BY USING DIFFERENT DIGESTION PROCEDURES
P. Mamatha*    [ Abstract ] -- [ Full Text - PDF ]

8. DEVELOPMENT AND VALIDATION OF GC METHOD FOR ESTIMATION OF LINDANE IN PHARMACEUTICAL FORMULATION
Harinder Singh*    [ Abstract ] -- [ Full Text - PDF ]

9. ANTI DIARRHOEAL ACTIVITY OF LEAF EXTRACTS Anogessius accuminata
K.Hemamalini*    [ Abstract ] -- [ Full Text - PDF ]

10. EFFECT OF GRAPE FRUIT ON BIOAVAILABILITY OF THE DRUGS
Srinivas Kotagiri*    [ Abstract ] -- [ Full Text - PDF ]

11. ORGANOGEL:  TOPICAL AND TRANSDERMAL DRUG DELIVERY SYSTEM
Kalpana D. Patil*    [ Abstract ] -- [ Full Text - PDF ]

12.
RP-HPLC-DAD METHOD FOR DETERMINATION OF IRBESARTAN IN BULK AND TABLETS EXPOSED TO FORCED CONDITIONS
Kamepalli Sujana*    [ Abstract ] -- [ Full Text - PDF ]

13. PRECLINICAL EVALUATION OF A POLYHERBAL FORMULATION ‘DM-99’ IN STREPTOZOTOCIN INDUCED DIABETIC RATS/MICE
Gupta K*    [ Abstract ] -- [ Full Text - PDF ]

14. PHYSICOCHEMICAL STANDARDIZATION OF ANDROGRAPHIS PANICULATA (NEES) : AN AYURVEDIC DRUG
Manoj Kumar Pandey*    [ Abstract ] -- [ Full Text - PDF ]

15. IN VITRO BACTERICIDAL ACTIVITY OF SEEDS EXTRACT OF NIGELLA SATIVA AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS ISOLATED FROM TERTIARY CARE HOSPITAL DELHI NCR REGION INDIA
Mohd Aslam*    [ Abstract ] -- [ Full Text - PDF ]

16. EXTRACTIVE SPECTROPHOTOMETRIC METHODS FOR NEBIVOLOL HYDROCHLORIDE
K.NARENDRA KUMAR REDDY*    [ Abstract ] -- [ Full Text - PDF ]

17. EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF FRUITS OF TRAPA NATANS LINN
Ami S. Patel*    [ Abstract ] -- [ Full Text - PDF ]

18. SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF ERLOTINIB IN PURE AND PHARMACEUTICAL DOSAGE FORMS
M.Padmalatha*    [ Abstract ] -- [ Full Text - PDF ]

19.EVALUATION OF HEPATOPROTECTIVE AND ANTIOXIDANT ACTIVITY OF ROOTS OF LAGERSTROEMIA SPECIOSA PERS
Pritikumari N. Lad*    [ Abstract ] -- [ Full Text - PDF ]

20. PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL POTENTIAL OF CHLOROFORM CRUDE EXTRACT OF PARKINSONIA ACULEATA LIN. (FAMILY- LEGUMINOSEAE) LEAVES AGAINST SOME BACTERIA CAUSING URINARY TRACT INFECTION (UTI) IN HUMANS
Priyam Singh*    [ Abstract ] -- [ Full Text - PDF ]

21. OCULAR INSERTS: AN OVERVIEW
Renu Kalyanwat*     [ Abstract ] -- [ Full Text - PDF ]

22. IN VITRO ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL CONSTITUENTS OF CROTON SCABIOSUS BEDD
Sarojini Devi. N*    [ Abstract ] -- [ Full Text - PDF ]

23. REVERSE PHASE HPLC MRTHOD FOR THE ANALYSIS OF CEFADROXIL IN PHARMACEUTICAL DOSAGE FORM
Sheetal Vikas Patil*    [ Abstract ] -- [ Full Text - PDF ]

24. SYNTHESIS OF SUBSTITUTED FLUORO PYRAZOLES FOR ANTI-BACTERIAL AND ANTI-OXIDANT ACTIVITY
Shivaji. B. Bole*    [ Abstract ] -- [ Full Text - PDF ]

25. RADICAL SCAVENGING ACTIVITY OF LEAVES AND RHIZOMES OF CURCUMA AMADA
Sivaprabha*    [ Abstract ] -- [ Full Text - PDF ]

26. PHYTOSOME: A NOVEL DRUG DELIVERY SYSTEM FOR IMPROVING BIOAVAILABILITY OF HERBAL MEDICINE
Srikanth.Vangapelli*    [ Abstract ] -- [ Full Text - PDF ]

27. EVALUATION OF NOOTROPIC POTENTIAL AND IN-VITRO ANTIOXIDANT ACTIVITY AQUEOUS EXTRACT OF ROOTS OF ASPARAGUS RACEMOSUS IN RATS
Sumalatha Gindi*    [ Abstract ] -- [ Full Text - PDF ]

28. DESIGN AND EVALUATION OF FLOATING DRUG DELIVERY BASED ON MATRIX TABLET OF ACYCLOVIR
Swapnil R. Zaware*    [ Abstract ] -- [ Full Text - PDF ]

29. DESIGN AND DEVELOPMENT OF ACECLOFENAC FAST DISSOLVING TABLETS BY AMORPHOUS SOLID DISPERSION TECHNIQUE USING MODIFIED AEGLE MARMELOS GUM
Upendra Kulkarni*    [ Abstract ] -- [ Full Text - PDF ]

30. TIPYRETIC AND ANTI-INFLAMMATORY ACTIVITIES OF TEPHROSIA PURPUREA ROOT EXTRACTS
Valli .G*    [ Abstract ] -- [ Full Text - PDF ]

31. NUCLEAR PHARMACY: AN UPDATED REVIEW
Verma Vikrant*    [ Abstract ] -- [ Full Text - PDF ]

32. DEVELOPMENT OF COLON TARGETED LORNOXICAM MATRIX TABLET
Vinod Dube*    [ Abstract ] -- [ Full Text - PDF ]


33. A REVIEW ON FLOATING DRUG DELIVERY SYSTEM AS A PART OF GRDDS
Vishal Christian*    [ Abstract ] -- [ Full Text - PDF ]

34. SIMULTANEOUS ESTIMATION OF OLMESARTAN MEDOXOMIL
AND HYDROCHLOROTHIAZIDE
IN TABLET DOSAGE FORM BY UV- SPECTROPHOTOMETRIC METHOD
Sonali  P. Mahaparale*    [ Abstract ] -- [ Full Text - PDF ]

35. FORMULATION AND PROCESS PARAMETERS OPTIMIZATION FOR ORODISPERSIBLE TABLET OF GRANISETRON HCl
Janak Jain*    [ Abstract ] -- [ Full Text - PDF ]

36. EVALUATION OF MICROCRYSTALLINE STARCH FROM SWEET POTATO IN DIRECT COMPRESSION OF RELATIVELY HIGH DOSE POORLY COMPRESSIBLE DRUG
Emmanuel O. Olorunsola*    [ Abstract ] -- [ Full Text - PDF ]



37. VISION OF RURAL PHARMACIST IN PATIENT COUNSELING AND CONTINUING  PHARMACY  EDUCATION PROGRAMS
Ranjeet B Ugale*   [ Abstract ] -- [ Full Text - PDF ]

38. FORMULATION DEVELOPMENT OF SELECTED DRUGS BY DIRECT COMPRESSION METHOD
K. P. R. Chowdary*   [ Abstract ] -- [ Full Text - PDF ]


39. MOUTH DISSOLVING TABLETS: A REVIEW
  Gajare G. G.*   [ Abstract ] -- [ Full Text - PDF ]