Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
In the present review, an attempt has been made to congregate the botanical, phytochemical, pharmacological information on Croton zambesicus, a medicinal plant that has wide application in African folkloric medicine. The phytochemical present in it lead to have a variety of biological/pharmacological activities such as antidiabetic, antiulcer, anticonvulsant, analgesic, anti-inflammatory, neuropharmacological, antimicrobial, antiplasmodial anticoagulant and vasorelaxant activities.
Key words: Croton zambesicus, Phytoconstituents, Pharmacological activities.
June 2011 Issue
June - 2011 / Volume - 3/Issue - 04
( Total Articles =30 )
June - 2011 / Volume - 3 / Issue - 04 / / Article No - 25 / Review Article
AN OVERVIEW- CROTON ZAMBESICUS MUELL.
Surjeet Kumar1*,Lincy Joseph1,
Mathew George1, Lakhvir Kaur1, Vasudha Abhi1
11School of Pharmaceutical Sciences,
Shoolini University, Solan (H.P.) India.