Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
The antipyretic activity of root tubers of Chlorophytum borivilianum Sant. & Fern. (Liliaceae) was evaluated by using methanolic extract in wister strain of albino rats. The methanolic extracts of Chlorophytum borivilianum (MECB) at doses of 200 & 400 mg/kg body weight were evaluated for antipyretic activity using Brewer’s yeast induced pyrexia. The two extracts showed significant reduction in yeast- provoked elevated temperature. The antipyretic effect of the extract was comparable to that of paracetamol (150mg/ kg body weight, P.O.)
Key words: Safed Musli, Chlorophytum borivilianum, Antipyretic, Brewer’s yeast, Pyrexia.
June 2011 Issue
June - 2011 / Volume - 3/Issue - 04
( Total Articles =30 )
Article No 22
June - 2011 / Volume - 3 / Issue - 04 / / Article No - 22 / Research Article
A STUDY ON ANTIPYRETIC ACTIVITY OF CHLOROPHYTUM BORIVILIANUM SANT. & FERN. ROOT TUBERS.
Das D.2, Tripathy N.K.3
1The Pharmaceutical College,
Samaleswari Vihar, Tingipali, Barpali - 768 029
2School of Pharmaceutical Sciences,
SOA University , Bhubaneswar -751 030
3Department of Zoology,
Berhampur University, Berhampur - 760 007