Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
This study was conducted to investigate the bioactive potential of coastal medicinal plants to develop alternative drug development for the treatment of diseases in aquaculture. Fifteen coastal medicinal plants / parts were investigated to evaluate the antibacterial activity against bacterial fish pathogens. Among the plants, Cinnamomum verum and Eupatorium odoratum, Azardirachta indica exhibited excellent antibacterial activity against 10 bacterial pathogens from diseased ornamental fishes under captivity.
Key words: Antibacterial sensitivity, Coastal Medicinal plants, Disc diffusion method, Ornamental fish bacterial pathogens
June 2011 Issue
June - 2011 / Volume - 3/Issue - 04
( Total Articles =30 )
Article No 16
June - 2011 / Volume - 3 / Issue - 04 / / Article No - 16 / Research Article
IN VITRO ANTIBACTERIAL ACTIVITY OF COASTAL MEDICINAL PLANTS AGAINST ISOLATED BACTERIAL FISH PATHOGENS
Ravikumar S*2, Anitha Anandha Gracelin N1,
Palani Selvan G2 and Kalaiarasi A2
1Marine Science and Technology, Manonmaniam Sundaranar
University, Rajakkamangalam, Tamil Nadu, India - 629502
2School of Marine Sciences, Department of
Oceanography and Costal Area Studies, Alagappa University,
Thondi Campus, Tamil Nadu, India - 623409