Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
Coleus aromaticus Benth. Of the family Labiatae is a large succulent aromatic herb used for flavouring drinks and medicine. The leaves are considered as carminative , digestive , anthelmintic and diuretic. The present study is dealt with the phytochemical screening , anthelmintic and antimicrobial activities of the leaf extracts and leaf oil. The leaf extracts with various solvents like petroleum ether, choloroform and methanol were prepared and both qualitative and quantitative tests for phytochemicals were done. It showed the presence of carbohydrates, proteins, phenols tannins flavanoids, saponins glycosides etc. in various quantities. On anthelmintic assay chloroform and methanol extract showed significant activity. Antibacterial activity of the essential oil was very promising. The plant extracts also showed antibacterial activities against the test organisms while the antifungal property was very poor.
Key words: Coleus aromaticus , anthelmintic, antibacterial, antifungal,
June 2011 Issue
June - 2011 / Volume - 3/Issue - 04
( Total Articles =30 )
Article No 14
June - 2011 / Volume - 3 / Issue - 04 / / Article No - 14 / Research Article
PHYTOCHEMICAL SCREENING , ANTIMICROBIAL AND ANTHELMINTHIC STUDIES ON COLEUS AROMATICUS BENTH.
Prameela T. S. *1,
Oommen P. Saj1
1Department. of Botany,
University College, Thiruvananthapuram, Kerala -695034.