Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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The present investigation was to analysis the phytochemical constituents of the bark of Naringi crenulata (Roxb.)Nicols. (Rutaceae). Preliminary phytochemical study was carried out in ethanol and water extracts indicated the presence of tannins, phenols, flavonoids, saponin , terpenoid, quinine, protein and carbohydrates. Pharmacognostic evaluation of bark powder was carried out to determine its macro morphological and chemomicrophological profiles. The present investigation reveals that the presence of many phytochemical constituents and they can be useful in curing some of human diseases.
Key words: Naringi crenulata, bark, phytochemical and pharmacognostical analysis.
May 2011 Issue
May - 2011 / Volume - 3/Issue - 03
( Total Articles =25 )
Article No 18
May - 2011 / Volume - 3 / Issue - 03 / Article No - 18 / Research Article
PRELIMINARY PHYTOCHEMICAL ANALYSIS AND PHARMACOGNOSTICAL INVESTIGATION ON BARK OF NARINGI CRENULATA (ROXB.)NICOLS.
1Department of Botany,Government
Arts College Tiruvannamalai, Tamilnadu
Department of Botany, Government
Arts College (Autonomous), Kumbakonam,