Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
The survey of literature showed that Allium sativum is a medicinal plant of interest due to its various reported activities such as antiatherogenic, antihypertensive, lipid-lowering, antiatherosclerotic, antiprotozoal, anthelmentic, antibacterial, antifungal, antiviral, recently developed as anticancerous and antithrombotic. It strongly indicates that garlic and its chemical compounds which elicit a wide range of biological activities associated with anticarcinogenesis and cancer prevention merit more focused attention. The Egyptians worshiped garlic and the Greek chewed it to get strength. In Asian countries it was recognized for its medicinal properties and also used as a flavoring agent for food. Now scientists have revealed many health protective effects of garlic including prevention of cancer. It has become quite evident that the white bulb of garlic, though not a cure-all for cancer, is packed with cancer chemo preventive substances and should prove to be not just a flavoring agent but also a natural cancer preventive formula. This beneficial plant part therefore is worthy of serious consideration for further investigation and clinical trials.
Key words: Garlic, anticancerous, allicin, antihypertensive.
April 2011 Issue
April - 2011 / Volume - 3/Issue - 02
( Total Articles =26 )
Article No 17
April - 2011 / Volume - 3 / Issue - 02 / Article No - 17 / Review Article
A REVIEW ON MEDICINAL PROPERTIES OF ALLIUM SATIVUM (GARLIC).
Prafulla Mane1*, Rahul Mayee1,
1SRM Clinical Research Services Pvt. Ltd.
10, Gurukunj Housing Society, Tilak Nagar,
Aurangabad - 431005 (MS)