Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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Cordia obliqua Willd. is an important medicinal plant belonging to the family Boraginaceae. It is considered as one of the controversial drug in ayurveda since more than one botanical source is assigned to the drug. To facilitate correct and easy identification of the drug. Pharmacognostical studies covering morphology, macro and microscopic anatomical studies of leaf, stem and root, organoleptic evaluation, fluorescence analysis, physico chemical characters of plant powder, mineral constituents and preliminary phytochemical screening of the plant, along with diagnostic character of this plant is presented. The study helps in the formulation of the drug.
Key words: Cordia obliqua, Anatomical studies. Pharmacognosy, Physico- chemical analysis, Phytochemical screening,
April 2011 Issue
April - 2011 / Volume - 3/Issue - 02
( Total Articles =26 )
Article No 22
April - 2011 / Volume - 3 / Issue - 02 / Article No - 22 / Research Article
STUDIES ON THE PHARMACOGNISTIC PROPERTIES OF CORDIA OBLIQUA Willd.
Dr. S. Ravikumar*1, M.Uthiraselvam2,
K. Natarajan3, M.Babuselvam2,E.Rajabudeen4
1School of Marine Sciences, Department of
Oceanography and CAS,
Alagappa University, Thondi Campus, Tamil Nadu, India.
2P.G.Department of Microbiology,
Dr.Zakir Husain College,
Ilayangudi, Sivagangai District, Tamil Nadu, India.
.3G and Research Department of Plant Biotechnology,
St.Xavier’s Collge (Autonomous), Palayamkottai, Tamil Nadu, India
4Department of Botany, Dr.Zakir Husain College, Ilayangudi, S
ivagangai District, Tamil Nadu, India