Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
India has a great wealth of various naturally occurring plant drugs which have great potential pharmacological activities .The root of clerodendron infortunatum Linn is used in south India as a remedy for various dieases.The study comprising taxonomy of the species ,macro and microscopical characters ,phytochemical and uv analysis of the root .Besides chromatographic details of root extract helps in the identification of the plant also contribute towards establishing pharmacopoeial standards .HPTLC studies helps to identify the species in drug form and to establish the biomarker compound .
Key words: Clerodendron infortunatum root ,Pharmacognosy, HPTLC.
April 2011 Issue
April - 2011 / Volume - 3/Issue - 02
( Total Articles =26 )
Article No 11
April - 2011 / Volume - 3 / Issue - 02 / Article No - 11 / Research Article
PHARMACOGNOSTIC,PHYTOCHEMICAL STUDIES ON THE ROOT OF CLERODENDRON INFORTUNATUM LINN
Leena P.N. *1,
Dr. N.A. Aley Kutty1, Santhosh M. Mathews1
1Pushpagiri College of Pharmacy,
Dept. of Pharmacognosy,
Medicity, Tiruvalla.Pathanamthitta Kerala