Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
Pongamia pinnata (Linn) belonging to the family Fabaceae (Papilionaceae) commonly known as Karanj. It is a small evergreen tree, which is widely distributed in India, Bangladesh, China, and Australia. The plants have been described as a useful remedy for foul ulcer, fistulous sores, gonorrhea and urethritis. Pharmacognostic investigation of fresh, powdered and anatomical sections of leaves were carried out to determine its macromorphological, micromorphological and chemomicromorphological profiles. Phytochemical investigation indicated the preparation of different extracts using different solvents and phytochemical tests for confirmation of the presence of alkaloids, tannins, flavonoids, steroids, glycosides & carbohydrates. The result of the study can be useful in setting some diagnostic indices for the identification and the preparation of the monograph of the plant.
Key words: Pongamia pinnata, Fabaceae, Tannins, Flavonoids.
April 2011 Issue
April - 2011 / Volume - 3/Issue - 02
( Total Articles =26 )
Article No 2
April - 2011 / Volume - 3 / Issue - 02 / Article No -2 / Research Article
PHARMACOGNOSTIC AND PHYTOCHEMICAL EVALUATION OF PONGAMIA PINNATA LINN FAMILY FABACEAE
Pankaj Khatri1, Rakesh Patel2,
Vaibhavi Jakhetia1, Sonu Sharma1
1Department of Pharmacognosy,
Suresh Gyan Vihar University, Jaipur, Rajasthan, India.
2Department of Pharmacognosy,
Ganpat University, Mehsana, Gujrat, India.