ABSTRACT

   Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.



        

Key words:
Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
Copyright 2009  by "International Journal of Pharmaceutica Research and Development"    All Rights reserved    E-Mail: info@ijprd.com
Welcome to "International Journal of Pharmaceutical Research and Development"  i.e. "IJPRD"
HOW TO PREPARE   
YOUR PAPER
What's New | Feedback | Copyright and Disclaimer
Online Since : March 2009
TODAY IS
Abstract Content
Model Abstract
Summary Content
Model Summary

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
- : BACK TO CURRENT ISSUE OF JOURNAL :-
((( PREVIOUS ARTICLE
NEXT ARTICLE )))
ABSTRACT
  
 
Screening and isolation of proteolytic bacteria was carried out from the soil samples collected from the surroundings of University College of Technology,Osmania University,Hyderabad.And identified as Bacillus subtilis SVR-07.The Bacillus subtilis SVR-07 could be  grow up to 60oC with in a broad pH range of 6.0 to 11.0 with an optimal growth temperature and pH at 55oC and 9.0 respectively.Different optimization parameters like Incubation period(48hrs), Inoculum level(3ml),Age of inoculum(24h),Effect of inhibitors(AgNO3) and different types of surfactants(Cetrimide) on alkaline protease production by using isolated Bacillus subtilis SVR-07.The results showed that the Bacillus subtilis SVR-07 under study are good producer of extra cellular protease at high temperature.This might be an indication that proteases produced would be thermo stable.



Key words:
Alkaline protease, Bacillus subtilis SVR-07, Submerged fermentation, Optimization

March - 2011 / Volume - 3/Issue - 1
( Total Articles =25 )
March 2011 Issue
[ VIEW FULL ARTICLE ] [PDF VIEW ]
Article No 21
March - 2011 / Volume - 3 / Issue - 01 / Article No - 21 / Research Article


EXTRACELLULAR ALKALINE PROTEASE PRODUCTION FROM ISOLATED  BACILLUS SUBTILIS SVR-07 BY USING SUBMERGED FERMENTATION

M.Narsi Reddy1*,

C. Ganesh Kumar1 K.Swathi2, B.Nagamani2,
S. Venkateshwar2, L.Venkateswar Rao3

1Chemical Biology,Indian Institute of Chemical Technology,
Hyderabad, India-500 007
2Centre for biotechnology, University College of Technology,
Osmania university, Hyderabad, 500 007,
Andhra Pradesh, India
3Department of Microbiology, Osmania university,
Hyderabad, 500 007, Andhra Pradesh, India
Email:mnreddydr@gmail.com
M. Narsi Reddy