Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
Enhancing the shelf life of any product with natural extract from fruits and vegetables is most desirable. These extracts with known and unknown bioactive compounds can also be exploited to inhibit the oxidation in human system. In the present study evaluation of the antioxidant potentials of selected fruits, vegetables, spices and medicinal plants available locally was carried out by five methods selected, which represents lipid peroxidation occurring in both food as well as in biological system. Neem leaves in medicinal plants, tomato and cabbage in vegetables, curry leaves in leafy vegetables, pomegranate and amla in fruits, coriander seed and decalepis rhizome showed very good antioxidant potency in most of the methods selected in the study, which were comparable to synthetic antioxidant such as BHA, TBHQ etc. Utilization of the extracts studied may result in formulating better health care products with enhanced shelf life and little or no side effects.
Key words: Antioxidants, Fruits, Vegetables, Medicinal plants, Spices, DPPH, ?-carotene bleaching, Metal chelating
March - 2011 / Volume - 3/Issue - 1
( Total Articles =25 )
March 2011 Issue
Article No 15
March - 2011 / Volume - 3 / Issue - 01 /Article No - 15 / Research Article
ANTIOXIDANT POTENTIAL OF SOME COMMON PLANT SOURCES
Siddalinga Swamy M1,Farhath khanum1
1Department of Biochemistry and Nutrition,
Defence Food Research Laboratory,
Siddartha Nagar, Mysore - 570 011,Karnataka, India