Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
Vinpocetine is a very effective tool used for memory enhancement. It is best known as cerebral vasodilator and very effective in age related memory impairment. Our memory starts decline after certain age it is basically due to damage of neurons, the drug vinpocetine has neuroprotective effect. So this drug is very effective in memory impairment. Vinpocetine dilates the blood vessels and increase the cerebral blood flow. In this review the pharmacokinetics pharmacodynemics, uses, clinical studies, adverse effects and research summary of vinpocetine are discussed.
Key words: Vinpocetine, cerebral vasodilator, neuroprotective, memory enhancement.
Article No 13
February - 2011 / Volume - 2 / Issue - 12 / Article No - 13 / Review Article
VINPOCETINE : A STEP TOWARDS MEMORY ENHANCEMENT
Preeti khulbe1*,Vijay Juyal1
1Department Of Pharmaceutical Sciences,
Faculty of Technology Bhimtal, Kumaon University
February - 2011 / Volume - 2/Issue - 12
( Total Articles =25 )
February 2011 Issue