Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
January - 2010 / Volume - 2/Issue - 11
( Total Articles =15 )
January 2011 Issue
A pharmacognostical studies of a plant enables the scientist for proper identification of a drug and removes adulteration and provide a basis for authentication of crude drug. By looking the high traditional use of crude drugs the present work and investigation of the plant drug Pterospermum Suberifolium Linn. and undertaken for research. Pterospermum Suberifolium Linn belonging to family sterculiaeace. It is moderate size or large tree with woody stem. Even though the plant has gained scientific importance recently, there is a need for pharmacognostical; standardization. Hence in present work the leaf part of the plant were subjected to various microscopical and physicochemical evaluations. In the microscopic studies different cell structure and arrangement were studied and physicochemical evaluation moisture content, ash value
and extractive values were studied.
Key words: Pterospermum Suberifolium Linn , Pharmacognostical, stomatal index, herbarium preparation, ash value
Article No 13
December - 2010 / Volume - 2 / Issue - 10 / Article No - 13 / Research Article
PHARMACOGNOSTICAL AND PHYSICOCHEMICAL EVALUATION OF PTEROSPERMUM SUBERIFOLIUM LINN LEAVES
Vibhor K. Jain1*, Bindu Jain,
1School of Pharmacy, Chauksey Engineering College,
Bilaspur (C.G), 495004
Only 15 Articles will be Published in Each Issues