Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
January - 2010 / Volume - 2/Issue - 11
( Total Articles =15 )
January 2011 Issue
Antibacterial activity of methanolic extract of Crataeva religiosa stem bark samples (Apical bark, meddle bark and Mature bark) was studied with respect to different pathogenic bacteria species Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klbecialla pneumoneae, Salmonela typhi, Proteus mirabilis and Micrococcus sp. The methanolic extract of apical bark was effective than the middle bark and mature bark in inhibiting the growth of all bacteria. The bacterium Staphylococcus aureus was most sensitive among all the bacterial species studied. Preliminary phytochemical analysis revealed the presence of alkaloids, glycosides, flavonoids, flavanols, phenols, saponins and terpenoids. The concentrations secondary metabolites was found higher in the apical stem bark than the middle and mature stem bark. The percent extract yield was maximum in apical stem bark.
Key words: Antibacterial activities, Crataeva religiosa, phytochemical analysis, extract yield and secondary metabolites.
Article No 12
January - 2011 / Volume - 2 / Issue - 11 / Article No - 12 / Research Article
DIFFERENTIAL BACTERICIDAL POTENTIAL AND PHYTOCHEMICAL EVALUATION OF CRATAEVA RELIGIOSA STEM BARK
Udaysing Hari Patil1,
Dattatraya K. Gaikwad 1
1Department Of Botany, Shivaji University
Kolhapur, Maharashtra INDIA 416001
Only 15 Articles will be Published in Each Issues