Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
January - 2010 / Volume - 2/Issue - 11
( Total Articles =15 )
January 2011 Issue
Present paper describes oil composition of the seed and leaves of Cynometra iripa Kostel. The analysis of fatty acids was performed following extraction in petroleum ether, and esterification using GC-FID. The saturated, monounsaturated and polyunsaturated fatty acid were found 39.3%, 18.2% and 42.4%respectively in seed oil and leaves oil content was 76.5%, 17.9% and 5.6% as saturated, monounsaturated and polyunsaturated fatty acids respectively. The major fatty acids in Cynometra iripa seeds oil were Linoleicacid, oleic acid, palmitic acid and caproic acid. However major components of leaves oil are palmitic acid, stearic acid, oleic acid, myristic acid. Stearic acid is observed in both, seed oil and leaf oil in appreciable quantities. This analysis reveals that seeds and leaves of Cynometra iripa serves as a source of essential fatty acids (C18: 2W6, C18:1w9).
Key words: Cynometra iripa Kostel,petroleum ether, Linoleicacid, oleic acid, palmitic acid and caproic acid, essential fatty acids (C18: 2W6, C18:1w9).
Article No 8
January - 2011 / Volume - 2 / Issue - 11 /Article No - 08/ Research Article
FATTY ACID PROFILE OF CYNOMETRA IRIPA KOSTEL FROM SEEDS AND LEAVES.
1Department of Botany, Shivaji University,
Only 15 Articles will be Published in Each Issues