Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.
Key words: Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
January - 2010 / Volume - 2/Issue - 11
( Total Articles =15 )
January 2011 Issue
Wedelia chinensis (Osbeck) Merr. is considered to be very effective jaundice plant in Indian indigenous system of medicine. The juice of the tender leaves is used efficaciously in jaundice; also crushed fresh leaves are used to treat helminthiasis. In Siddha system of medicine, it is used for hair growth stimulant and hair dying. In order to ensure the use of only genuine and uniform material in preparation of herbal formulation, work on standardization was carried out. Morphological and anatomical aspects as well as Microscopical characteristics have been worked out to identify the diagnostic features of the plant. Physical constant values involving moisture content, ash and extractives as well as qualitative and quantitative estimation of various phytochemical have been studied. The presence of Saponins, Tannins, Terpenoids, Steroid, Flavonoids, and some other chemical constituents are recorded.
Key words: Wedelia chinensis (Osbeck) Merr, Macroscopical, Microscopical, Phytochemical, Jaundice.
Article No 7
January - 2011 / Volume - 2 / Issue - 11 / Article No - 7 / Research Article
PHARMACOGNOSTICAL STUDIES OF THE PLANT WEDELIA CHINENSIS
R. Mohan Kumar*1, V. Suresh1, S. V. Rajesh2,
N. Senthil Kumar1,G. Arunachalam3
1JKK Munirajah Medical Research Foundation
College of Pharmacy, Komarapalayam, Namakkal,
Tamil Nadu. India
2Vivekananda College of Arts & Sciences for Women,
Trichengode, Namakkal, Tamil Nadu, India
3PGP College of Pharmaceutical Sciences &
Research Institute, Namakkal, Tamil Nadu,India
R. Mohan Kumar
Only 15 Articles will be Published in Each Issues