ABSTRACT

   Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.



        

Key words:
Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
Copyright © 2009  by "International Journal of Pharmaceutica Research and Development"  ∑  All Rights reserved  ∑  E-Mail: info@ijprd.com
Welcome to "International Journal of Pharmaceutical Research and Development"  i.e. "IJPRD"
HOW TO PREPARE   
YOUR PAPER
What's New | Feedback | Copyright and Disclaimer
Online Since : March 2009
TODAY IS
Abstract Content
Model Abstract
Summary Content
Model Summary

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
- : BACK TO CURRENT ISSUE OF JOURNAL :-
((( PREVIOUS ARTICLE
NEXT ARTICLE )))
[ VIEW FULL ARTICLE ] [PDF VIEW ]
December - 2010 / Volume - 2/Issue - 10
( Total Articles =17 )
December 2010 Issue
Past Issues

March 2009

April 2009

May 2009

June 2009

July 2009

August 2009

September 2009

October 2009

November 2009

December 2009

January 2010

February 2010

March 2010

April 2010

May 2010

June 2010

July 2010

August 10

September 10

October 10

November 10


December 2010
Article No 4
December - 2010 / Volume - 2 / Issue - 10 / Article No - 4 / Review Article

FERRO FLUIDS: A PROMISING DRUG CARRIER : A REVIEW


Miss. Sonal A. Patil
1*, Mr. H. P. Suryawanshi1,
Mr. Sunil R. Bakliwal1, Dr. Sunil P. Pawar1.


1P. S. G. V. P. Mís College of Pharmacy,
Tal-Shahada, Dist-Nandurbar, 425 409.
Email : Sonalpharma02@gmail.com
Sonal Patil
ABSTRACT

   Drug targeting is delivery of drug to receptor, organ or to any other specific part of body exclusively. Various non-magnetic micro-carriers like liposomeís, nano-particles, microspheres, micro-particles are successfully utilized for drug targeting but it seemed to have poor specificity and rapidly cleared off by RES (Reticulo-Endothelial System) under normal circumstances. Magnetism plays a very important role in this case. The field of magnetic micro sphere was pioneered in US by Dr. Kenneth Widder and his colleagues in late 1970ís.  Magnetic field is believed to be harmless to biological system and adaptable to any part of body. Up to 60% of an injected dose can be deposited and released in controlled manner in selected surface. After administration of that formulated drug place a magnet on body site where one need action. Due to magnetic property drug, get attracted to that site either via enzymatic activity or changes in physiological condition like pH, osmolality, temperature and be taken up by tumour cells.  It is a challenging area for future research and holds lots of promises for novel and efficient approach for targeted drug delivery system. This review focuses on drug targeting by Magnetic Microspheres, various magnetic carriers and their characterization.

        

Key words:
magnetic microsphere, magnetic targeted carriers, targeted drug delivery, characterization.
.