ABSTRACT

   Typhoid fever (TF) is an acute systemic infection caused by Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B. It is transmitted by the fecal oral route mainly via contaminated food and water. The developing countries have high rate of morbidity and mortality due to Typhoid fever, epidemics take place in developed world also. There are increased incidences of multi drug resistant in S. typhi strains that has further complicated its management and only a few antibiotics are now effective in treatment of typhoid. We report that the aqueous extracts of fruit peel Citrus sinensis (L.) confer anti typhoid activity against Salmonella Typhi, Salmonella Para Typhi A and Salmonella Para Typhi B respectively on comparison with ciprofloxacin.



        

Key words:
Typhoid fever, Salmonella Typhi, Salmonella Para Typhi A , Salmonella Para Typhi B, anti typhoid activity, Citrus sinensis.
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December - 2010 / Volume - 2/Issue - 10
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December 2010
Article No 01
December - 2010 / Volume - 2 / Issue - 10 / Article No - 01 / Research Article

CHARACTERIZATION OF FATTY ACID METHYL ESTER CONTENTS OF CORDIA MACLEODII (HOOK.F.& THOMSON) BARK BY GAS CHROMATOGRAPHY - MASS SPECTROMETRY

Pankaj B. Nariya*1,
Nayan R. Bhalodia1,
V.J.Shukla2, R.N.Acharya3

1Research Scholar in phyto chemistry,
I.P.G.T. & R.A.-G.A.U.. Jamnagar
Gujrat, India
2Head of the Department Pharmaceutical
Laboratory, I.P.G.T. & R.A.-G.A.U.. Jamnagar
Gujrat, India
3Reader, Department of Dravyaguna, GAU jamnagar, India
     Email:pankajnariya@yahoo.co.in
Pankaj Naria
ABSTRACT

The investigation was carried out to determine The chemical composition of the fatty acids methyl esters (FAMEs) bark of Cordia Macleodii were analyzed by gas chromatography-mass spectrometry (GC-MS). GC-MS analysis of Methyl ester of Saponifiable matter led to identification of 12 compounds. This analysis revealed that contains Cordia Macleodii bark mainly Butyric Acid-2, 2 di methyl vinyl ester (19.52%), Butyl Carbinol(14.58%) Gem-Di methyl Cyclopentane (14.34%), Hexadecane (14.01%) , Ciclosano (19.71%) , Heptadeconoic Acid(9.18%).
        

Key words:
Cordia Macleodii, GC-MS analysis.