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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
Patient compliance can be increased and adulteration can be decreased in Ayurvedic powders by formulating them into tablets. Attempts have been made for the development of fast disintegrating tablets of Amla powder by vacuum drying technique. Amla powder is generally used to enhance digestion, treat constipation, to reduce fever and cough and as a blood purifier. Amla powder is mainly indicated for dyslipidaemia and oxidative stress in the ageing process. The granules containing the drug and excipients were examined for the precompretional parametes. The prepared formulations were evaluated for hardness, weight variation, friability, disintegration and wetting time. The values of precompressional parameters were within prescribed B.P. limits and indicates good free flowing properties. In all the formulations friability was less than 1% indicates tablets had a good mechanical resistance. Hardness of the tablets was found to be in the range of 3.50 - 4.60 kg/cm2. The disintegration and wetting times of all formulations were decreased with increase in the concentration of subliming agents.
Key words: Fast-disintegtrating tablets, Camphor, Amla powder, Kyron T-314, Kyron T-114.
November - 2010 / Volume - 2/Issue - 9
( Total Articles =31 )
November 2010 Issue
Article No 20
November - 2010 / Volume - 2 / Issue - 9 / Article No - 20 / Research Article
DESIGN AND DEVELOPMENT OF FAST DISINTIGRATING TABLETS CONTAINING AMLA POWDER BY VACUUM DRYING TECHNIQUE
Upendra Kulkarni*, Basawaraj S. Patil,
Prakash G. Korwar, Vipul Karkar
1RMESíS College of Pharmacy, Gulbarga-585102