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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
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ABSTRACT

   Human infections, particularly those involving the skin and mucosal surface constitute a serious problem, especially in tropical and subtropical countries. There has been a worldwide move towards the use of traditional medicines due to concerns over the more invasive, expensive and potentially toxic mainstream practices.  In the present study aqueous and ethanolic extracts of Triphala and its individual components (T. chebula, T. belerica and E. officinalis) were tested against the fungus Trichophyton rubrum, Microsporum canis  and Aspergillus fumigates. Result showed ethanolic extract had high inhibitory action against the studied fungus when compared to aquesous extract. In both aqueous and ethanolic extract T. chebula showed high inhibitory activity followed by T. belerica, Triphala formulation and E. officinalis. The present study revealed that both individual and combined aqueous and ethanolic extracts of Triphala shown anti-fungal activity and this study also revealed ethanolic extract is an ideal solvent.





        

Key words:
Triphala;  T. chebul;, T. belerica; E. officinalis; Anti-fungal activity

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October - 2010 / Volume - 2/Issue - 8
( Total Articles =20 )
October 2010 Issue
Article No 10
October - 2010 / Volume - 2 / Issue - 8 / Article No - 10 / Review Article

ANTI-FUNGAL ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACT OF TRIPHALA AND ITS INDIVIDUAL FRUIT COMPONENTS


R.Srikumar1*
, R.Sheela Devi2,
S.R.Ayyappan3,
R.Thangaraj4, R.Jegadeesh5, L. Hariprasath5


1Bharathidasan University College for Women,
Orathanadu-614 625, Thanjavur, Tamilnadu, India
2Dr.ALM.PG.IBMS, University of Madras, Taramani, Chennai, India.
3Sathyabama University Dental College & Hospital, Jeppiaar  Nagar, Old,
Mahabalipuram Road, Chennai 600 119.
4Ecoscience Research Foundation, East Coast Road,
Palavakkam, Chennai 600041, Tamil Nadu, India.
5Center for Advance Studies in Botany, University Of Madras, Guindy Campus
Chennai- 600 025, Tamil Nadu, India.
Email:rsrikumar_2003@yahoo.co.in

R. Srikumar