Copyright 2009  by "International Journal of Pharmaceutica Research and Development"    All Rights reserved    E-Mail: info@ijprd.com
Welcome to "International Journal of Pharmaceutical Research and Development"  i.e. "IJPRD"
HOW TO PREPARE   
YOUR PAPER
What's New | Feedback | Copyright and Disclaimer
TODAY IS
Abstract Content
Model Abstract
Summary Content
Model Summary

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
Copyright 2009  by "International Journal of Pharmaceutica Research and Development"    All Rights reserved    E-Mail: info@ijprd.com
Welcome to "International Journal of Pharmaceutical Research and Development"  i.e. "IJPRD"
HOW TO PREPARE   
YOUR PAPER
What's New | Feedback | Copyright and Disclaimer
Online Since : March 2009
TODAY IS
Abstract Content
Model Abstract
Summary Content
Model Summary

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
DEVELOPED AND VALIDATED Q-ABSORPTION RATIO METHOD FOR THE SIMULTANEOUS ESTIMATION OF LOTEPREDNOL ETABONATE AND MOXIFLOXACIN HCL IN THE PHARMACEUTICAL DOSAGE FORM

Barot Gaurang*1
,
Sharma Sandip1, Multani Parmeshwari1, Bhadani Shweta1

1
Department of Quality Assurance,  Saraswati Institute of Pharmaceutical Sciences, Dhanap, Gandhinagar
May - 2013 / Volume - 5/Issue - 3
( Total Articles =20)
May 2013 Issue
ABSTRACT
Loteprednol Etabonate and Moxifloxacin HCl are available in the market as combined ophthalmic formulation in ratio of 1:1 for the treatment of Post-operative inflammatory condition. The aim of the present work was to develop a simple, precise, sensitive and economical UV-Spectrophotometric method for the simultaneous estimation of Loteprednol Etabonate and Moxifloxacin HCl in the combined formulation. The wavelengths selected were 242.60 nm (
?max of Loteprednol Etabolate) and 265 nm (Iso-absorptive point). Beers law was followed in the range of 5-30 g/ml for both the drugs Loteprednol Etabonate and Moxifloxacin HCl with good recovery results for the accuracy. The reproducibility of the method was determined (Interday and Intraday), the relative standard deviation was found to be below 2%. The method was validated as per ICH guideline and successfully applied for the formulation analysis. A simple, accurate, precise, sensitive and economical UV Spectrophotometric method for the simultaneous estimation of Loteprednol Etabonate and Moxifloxacin HCl in the combined formulation has been developed.

KEYWORDS :
:  Moxifloxacin Hydrochloride, Loteprednol Etabonate, Q-absorption ratio metho
[ Full Text - PDF ]
Share This Article on Social Networking's or You can invite friends to this Article.  !!